RESEARCH USE ONLY
For qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Not evaluated by the FDA. Purchasers must be 21 years of age or older.
GHK-Cu
Certificate of Analysis
GHK-Cu
Tested batch: GHK-Cu 50mg — Janoshik test #169279
This material was independently verified by Janoshik Analytical, a third-party laboratory. View the full lab report with purity results on their verification portal:
View verified lab report →For laboratory research use only. Not for human consumption.
U.S. shipping: $8 flat standard (3–5 business days). Orders $100+ ship free. Most in-stock weekday orders are handed to the carrier the same business day.
GHK-Cu (copper tripeptide-1) is a naturally occurring copper-binding peptide studied in laboratory research for its interaction with cellular repair and gene-expression pathways. Research models have examined its role in collagen-synthesis signaling, antioxidant-pathway activity, and tissue-remodeling processes. Supplied as lyophilized material for qualified in-vitro research.
Compound specifications: Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.
Handling and storage
Supplied as lyophilized (freeze-dried) material. Store under the conditions printed on the product label and use laboratory handling procedures appropriate to your work. Every vial is labeled with lot information for batch traceability.
Research use notice
Reserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.
What is GHK-Cu?
GHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine (GHK), a tripeptide first identified in human plasma in the 1970s. GHK's high affinity for copper ions and its decline with age in circulation — documented in the literature — made the complex a long-running subject of skin, remodeling, and gene-expression research.
Published studies examine GHK-Cu across cell-culture, tissue, and animal models, including work on extracellular-matrix organization and broad gene-expression modulation. It is supplied here as high-purity lyophilized material strictly for qualified research use.
Mechanism of Action — Research Overview
In research models, GHK acts as a copper-delivery and -modulation peptide: it binds Cu(II) with high affinity and is studied for how that complex influences copper-dependent enzymes, antioxidant-pathway markers, and matrix-metalloproteinase/TIMP balance in tissue models.
Gene-expression studies (notably the Broad Institute connectivity-map analyses discussed in the literature) report GHK-associated modulation of a wide panel of genes involved in tissue organization and stress response — a systems-level profile rather than single-target activity.
Research Applications
- Copper-transport and metallopeptide chemistry research
- Extracellular-matrix and remodeling-pathway studies
- Skin and fibroblast research models
- Gene-expression modulation studies
- Antioxidant-pathway and stress-response research
GHK-Cu Specifications
| Format | Lyophilized powder in sealed 3 mL glass vial (50mg / 100mg) |
| CAS Number | 49557-75-7 |
| Chemical Formula | C14H23CuN6O4 (complex) |
| Molecular Weight | ≈ 402.9 g/mol |
| PubChem CID | 71587328 |
| Synonyms | Copper tripeptide-1, Glycyl-L-histidyl-L-lysine copper(II) complex |
| Storage | Store lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol. |
Laboratory Handling & Storage
Standard handling for lyophilized metallopeptides: sterile technique, PPE, protection from light and moisture, documented lot tracking.
Certificate of Analysis & Quality Assurance
Every batch of GHK-Cu is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: view batch COA. Documentation of lot number, test date, and method accompanies each batch.
References
- The potential of GHK as an anti-aging peptide. Aging Pathobiol Ther. 2020. PMID: 35083444
- GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015. PMID: 26236730
Note: GHK-Cu is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.
Shipping, Handling & Guarantee
- Fast U.S. shipping: Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.
- Lab safety profile: Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.
- Order guarantee: If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our Return & Refund Policy.