PP-S31 | Prestige Peptides

SS-31

10mg / 1 Vial
$50.00
Sale price  $50.00 Regular price 
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SS-31

RESEARCH USE ONLY

For qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Not evaluated by the FDA. Purchasers must be 21 years of age or older.

SS-31

$50.00
Sale price  $50.00 Regular price 
Size10mg
Amount
Bundle & save 3-vial packs 15% off · 5-vial packs 25% off · 10-vial packs 35% off — already applied in pack prices
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U.S. shipping: $8 flat standard (3–5 business days). Orders $100+ ship free. Most in-stock weekday orders are handed to the carrier the same business day.

SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide studied in laboratory research for its interaction with cardiolipin and mitochondrial membrane-function models. Supplied as lyophilized material for qualified in-vitro research.

Compound specifications: Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.

Research use notice

 

Reserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.

What is SS-31?

SS-31 (elamipretide; also known in the literature as MTP-131 and Bendavia) is a synthetic mitochondria-targeted tetrapeptide with the sequence D-Arg-2′,6′-dimethylTyr-Lys-Phe-NH2. Its defining research feature is selective association with cardiolipin, a phospholipid unique to the inner mitochondrial membrane.

Because of that membrane-targeting behavior, SS-31 has become a widely used probe in mitochondrial-structure and bioenergetics research, with a literature base spanning cellular models through late-stage clinical-development publications. It is supplied here as high-purity lyophilized material strictly for qualified research use.

Mechanism of Action — Research Overview

In research models, SS-31 concentrates at the inner mitochondrial membrane, where it binds cardiolipin and is studied for its influence on cristae architecture, electron-transport-chain organization, and membrane-potential stability under stress conditions.

Studies also examine its interaction with cytochrome c–cardiolipin binding and its effects on reactive-oxygen-species generation at the membrane level. Unlike broad antioxidants studied in research, SS-31's interest lies in its precise subcellular localization.

Research Applications

  • Mitochondrial membrane and cristae-architecture research
  • Cardiolipin-interaction and bioenergetics studies
  • Oxidative-stress response models
  • Ischemia-reperfusion research models
  • Cellular senescence and age-related mitochondrial-decline studies

SS-31 Specifications

Format Lyophilized powder in sealed 3 mL glass vial (10mg)
CAS Number 736992-21-5
Chemical Formula C32H49N9O5
Molecular Weight ≈ 639.8 g/mol
PubChem CID 11764719
Synonyms Elamipretide, MTP-131, Bendavia, D-Arg-Dmt-Lys-Phe-NH2
Storage Store lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.

Laboratory Handling & Storage

Standard small-peptide handling: sterile technique, PPE, protection from light and moisture, and documented lot tracking for reproducibility.

Certificate of Analysis & Quality Assurance

Every batch of SS-31 is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: view batch COA. Documentation of lot number, test date, and method accompanies each batch.

References

  1. Elamipretide: A Review of Its Structure, Mechanism of Action, and Therapeutic Potential. Int J Mol Sci. 2025. PMID: 39940712
  2. Elamipretide: First Approval. Drugs. 2026. PMID: 41335372

Note: SS-31 is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.

Shipping, Handling & Guarantee

  • Fast U.S. shipping: Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.
  • Lab safety profile: Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.
  • Order guarantee: If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our Return & Refund Policy.

 

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