PP-TB500 | Prestige Peptides

TB-500

10mg / 1 Vial
$40.00
$40.00
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TB-500
TB-500

RESEARCH USE ONLY

For qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Not evaluated by the FDA. Purchasers must be 21 years of age or older.

TB-500

$40.00
$40.00
Size10mg
Amount
Bundle & save 3-vial packs 15% off · 5-vial packs 25% off · 10-vial packs 35% off — already applied in pack prices
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U.S. shipping: $8 flat standard (3–5 business days). Orders $100+ ship free. Most in-stock weekday orders are handed to the carrier the same business day.

TB-500 is a synthetic peptide fragment based on the active region of thymosin beta-4. Research literature has examined its role in actin-binding activity, cell-migration models, and tissue-repair signaling pathways. Supplied as lyophilized material for qualified in-vitro research.

Compound specifications: Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.

Research use notice

Reserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.

What is TB-500?

TB-500 is a synthetic peptide based on the active region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid actin-binding protein found in virtually all mammalian cell types studied. The TB-500 designation in research supply refers to the synthetic fragment built around Tβ4's characterized actin-binding motif.

Thymosin Beta-4 has a broad published literature in cell-migration, angiogenesis, and tissue-organization research models, and TB-500 is studied as its practical research proxy. It is supplied here as high-purity lyophilized material strictly for qualified research use.

Mechanism of Action — Research Overview

The parent protein's best-characterized research role is regulation of actin dynamics: Tβ4 binds monomeric G-actin and influences the balance between actin polymerization and sequestration, a core determinant of cell shape, motility, and migration in experimental systems.

Research models additionally examine Tβ4-region peptides in relation to angiogenic signaling, extracellular-matrix organization, and inflammatory-response modulation — typically framed as multi-pathway effects rather than single-receptor pharmacology.

Research Applications

  • Actin-dynamics and cytoskeletal-organization research
  • Cell-migration and motility studies
  • Angiogenic-signaling research models
  • Soft-tissue and extracellular-matrix research
  • Comparative studies with BPC-157 and blended-peptide models

TB-500 Specifications

Format Lyophilized powder in sealed 3 mL glass vial (10mg)
Parent Compound Thymosin Beta-4 — CAS 77591-33-4; formula C212H350N56O78S; ≈ 4963.4 g/mol; PubChem CID 45382195
Synonyms Thymosin Beta-4 fragment, Tβ4 peptide
Storage Store lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.

Laboratory Handling & Storage

Standard lyophilized-peptide handling: sterile technique, PPE, moisture protection, and lot documentation.

Certificate of Analysis & Quality Assurance

Every batch of TB-500 is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: view batch COA. Documentation of lot number, test date, and method accompanies each batch.

References

  1. Thymosin β(4) and β(10) Expression in Human Organs during Development: A Review. Cells. 2024. PMID: 38994967
  2. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. Int Immunopharmacol. 2023. PMID: 36709593

Note: TB-500 is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.

Shipping, Handling & Guarantee

  • Fast U.S. shipping: Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.
  • Lab safety profile: Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.
  • Order guarantee: If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our Return & Refund Policy.

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