{"product_id":"pp-13","title":"NAD+","description":"\u003cp\u003eNAD+ (nicotinamide adenine dinucleotide) is an essential cellular coenzyme involved in redox reactions and energy metabolism. Laboratory research has explored its role in sirtuin and PARP pathway activity, mitochondrial function models, and age-related cellular research. Supplied as lyophilized material for qualified in-vitro research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCompound specifications:\u003c\/strong\u003e Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.\u003c\/p\u003e\u003cdiv class=\"pp-product-notes\"\u003e\n\u003cdiv class=\"pp-product-notes__item\"\u003e\n\u003cp class=\"pp-product-notes__label\"\u003eResearch use notice\u003c\/p\u003e\n\u003cp\u003eReserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\n\u003ch2\u003eWhat is NAD+?\u003c\/h2\u003e\n\u003cp\u003eNAD+ (β-nicotinamide adenine dinucleotide) is a ubiquitous cellular coenzyme central to redox metabolism and an obligatory substrate for sirtuins, PARPs, and other NAD-dependent enzymes studied across aging and metabolism research. It is one of the most referenced metabolites in the biochemical literature.\u003c\/p\u003e\n\u003cp\u003eResearch interest in NAD+ has intensified around age-associated declines in cellular NAD+ pools observed in study models, and around the NAD+ salvage and de-novo synthesis pathways that maintain them. It is supplied here as high-purity lyophilized material strictly for qualified research use.\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action — Research Overview\u003c\/h2\u003e\n\u003cp\u003eNAD+ functions in research systems as an electron carrier in glycolysis, the TCA cycle, and oxidative phosphorylation, cycling between oxidized (NAD+) and reduced (NADH) states. Beyond redox chemistry, studies examine its role as a consumed substrate for sirtuin deacetylases and PARP DNA-repair enzymes, linking NAD+ availability to gene-regulation and stress-response pathways.\u003c\/p\u003e\n\u003cp\u003ePublished models also investigate NAD+\/NADH ratio dynamics, mitochondrial NAD+ compartmentalization, and the influence of precursor availability (NR, NMN, nicotinamide) on intracellular NAD+ pools.\u003c\/p\u003e\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCellular redox metabolism and bioenergetics research\u003c\/li\u003e\n\u003cli\u003eSirtuin and PARP enzyme-substrate studies\u003c\/li\u003e\n\u003cli\u003eNAD+ salvage-pathway and precursor research\u003c\/li\u003e\n\u003cli\u003eMitochondrial function models\u003c\/li\u003e\n\u003cli\u003eAge-related metabolic research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eNAD+ Specifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilized powder in sealed glass vial (500mg \/ 1000mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e53-84-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChemical Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC21H27N7O14P2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 663.4 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5892\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eβ-NAD, Coenzyme 1, Diphosphopyridine nucleotide (DPN)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStore lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eLaboratory Handling \u0026amp; Storage\u003c\/h2\u003e\n\u003cp\u003eHandle as a standard hygroscopic research compound: minimize moisture exposure, use sterile technique and PPE, and document preparation conditions and lot numbers.\u003c\/p\u003e\n\u003ch2\u003eCertificate of Analysis \u0026amp; Quality Assurance\u003c\/h2\u003e\n\u003cp\u003eEvery batch of NAD+ is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: \u003ca href=\"https:\/\/verify.janoshik.com\/tests\/169302-NAD_500mg_NJ500_B4WA5G4TN6J1\" target=\"_blank\" rel=\"noopener\"\u003eview batch COA\u003c\/a\u003e. Documentation of lot number, test date, and method accompanies each batch.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eNAD(+) metabolism and its roles in cellular processes during ageing. \u003cem\u003eNat Rev Mol Cell Biol\u003c\/em\u003e. 2021. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33353981\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 33353981\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update. \u003cem\u003eAdv Nutr\u003c\/em\u003e. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37619764\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 37619764\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eNote: NAD+ is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eShipping, Handling \u0026amp; Guarantee\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast U.S. shipping:\u003c\/strong\u003e Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLab safety profile:\u003c\/strong\u003e Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder guarantee:\u003c\/strong\u003e If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our \u003ca href=\"\/policies\/refund-policy\"\u003eReturn \u0026amp; Refund Policy\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Prestige Peptides","offers":[{"title":"500mg \/ 1 Vial","offer_id":50520205787379,"sku":"pp-nd-500-1v","price":55.0,"currency_code":"USD","in_stock":true},{"title":"500mg \/ 3 Vials","offer_id":50240967835891,"sku":"pp-nd-500-3v","price":140.25,"currency_code":"USD","in_stock":true},{"title":"500mg \/ 5 Vials","offer_id":50240967868659,"sku":"pp-nd-500-5v","price":206.25,"currency_code":"USD","in_stock":true},{"title":"500mg \/ 10 Vials","offer_id":50279142228211,"sku":null,"price":357.5,"currency_code":"USD","in_stock":true},{"title":"1000mg \/ 1 Vial","offer_id":50520205852915,"sku":"pp-nd-1000-1v","price":90.0,"currency_code":"USD","in_stock":true},{"title":"1000mg \/ 3 Vials","offer_id":50240967934195,"sku":"pp-nd-1000-3v","price":229.5,"currency_code":"USD","in_stock":true},{"title":"1000mg \/ 5 Vials","offer_id":50240967966963,"sku":"pp-nd-1000-5v","price":337.5,"currency_code":"USD","in_stock":true},{"title":"1000mg \/ 10 Vials","offer_id":50279142260979,"sku":null,"price":585.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0839\/9857\/2787\/files\/nad-approved-wider-panel_5a2431c1-1415-4b74-99c4-23c624512a43.png?v=1788221466","url":"https:\/\/prestigepeptides.us\/products\/pp-13","provider":"Prestige Peptides","version":"1.0","type":"link"}