{"product_id":"pp-11","title":"Tesamorelin","description":"\u003cp\u003eTesamorelin is a synthetic 44-amino-acid analog of growth hormone-releasing hormone (GHRH) used in laboratory research on the growth-hormone axis. Published studies have examined its effects on GH pulsatility and downstream IGF-1 signaling in research models. Supplied as lyophilized material for qualified in-vitro research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCompound specifications:\u003c\/strong\u003e Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.\u003c\/p\u003e\u003cdiv class=\"pp-product-notes\"\u003e\n\n\u003cdiv class=\"pp-product-notes__item\"\u003e\n\u003cp class=\"pp-product-notes__label\"\u003eResearch use notice\u003c\/p\u003e\n\u003cp\u003eReserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\n\u003ch2\u003eWhat is Tesamorelin?\u003c\/h2\u003e\n\u003cp\u003eTesamorelin is a synthetic 44-amino-acid analog of human growth hormone–releasing hormone (GHRH 1-44), modified with an N-terminal trans-3-hexenoyl group that increases its stability against enzymatic degradation in research settings. It is one of the most extensively studied GHRH-axis compounds, with a published literature base spanning endocrinology and metabolism research.\u003c\/p\u003e\n\u003cp\u003eLaboratory interest in tesamorelin centers on its role as a defined, well-characterized probe of the GHRH\/GH\/IGF-1 signaling axis. It is supplied here as high-purity lyophilized material strictly for qualified research use.\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action — Research Overview\u003c\/h2\u003e\n\u003cp\u003eTesamorelin binds the GHRH receptor on pituitary somatotroph cell models, stimulating cAMP-mediated signaling that drives pulsatile growth-hormone release in experimental systems. Downstream, research models examine hepatic IGF-1 production and the feedback architecture of the somatotropic axis.\u003c\/p\u003e\n\u003cp\u003eBecause its action remains within the endogenous feedback loop in study models — rather than bypassing it — tesamorelin is frequently used to study physiologic versus pharmacologic growth-hormone-axis modulation.\u003c\/p\u003e\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eGHRH\/GH\/IGF-1 axis signaling research\u003c\/li\u003e\n\u003cli\u003eSomatotroph receptor pharmacology studies\u003c\/li\u003e\n\u003cli\u003ePulsatile hormone-release modeling\u003c\/li\u003e\n\u003cli\u003eEndocrine feedback-loop investigations\u003c\/li\u003e\n\u003cli\u003eMetabolic research models involving growth-hormone signaling\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTesamorelin Specifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilized powder in sealed 3 mL glass vial (10mg \/ 20mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e218949-48-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChemical Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC221H366N72O67S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 5135.9 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e16137828\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eGHRH(1-44) analog, TH9507, trans-3-hexenoyl-GHRH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStore lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eLaboratory Handling \u0026amp; Storage\u003c\/h2\u003e\n\u003cp\u003eStandard lyophilized-peptide handling applies: sterile technique, PPE, minimized moisture exposure during reconstitution, and documented lot tracking.\u003c\/p\u003e\n\u003ch2\u003eCertificate of Analysis \u0026amp; Quality Assurance\u003c\/h2\u003e\n\u003cp\u003eEvery batch of Tesamorelin is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: \u003ca href=\"https:\/\/verify.janoshik.com\/tests\/169220-Tesamorelin_10mgTSM10_VVWARUIR7TKS\" target=\"_blank\" rel=\"noopener\"\u003eview batch COA\u003c\/a\u003e. Documentation of lot number, test date, and method accompanies each batch.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eTesamorelin. \u003cem\u003e\u003c\/em\u003e. 2012. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31644039\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 31644039\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEfficacy and safety of tesamorelin in people with HIV on integrase inhibitors. \u003cem\u003eAIDS\u003c\/em\u003e. 2024. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38905488\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 38905488\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eNote: Tesamorelin is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eShipping, Handling \u0026amp; Guarantee\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast U.S. shipping:\u003c\/strong\u003e Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLab safety profile:\u003c\/strong\u003e Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder guarantee:\u003c\/strong\u003e If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our \u003ca href=\"\/policies\/refund-policy\"\u003eReturn \u0026amp; Refund Policy\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Prestige Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50520205590771,"sku":"pp-tsa-10-1v","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50240947814643,"sku":"pp-tsa-10-3v","price":153.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 5 Vials","offer_id":50240948109555,"sku":"pp-tsa-10-5v","price":225.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50279142031603,"sku":null,"price":390.0,"currency_code":"USD","in_stock":true},{"title":"20mg \/ 1 Vial","offer_id":50520205689075,"sku":"pp-tsa-20-1v","price":90.0,"currency_code":"USD","in_stock":false},{"title":"20mg \/ 3 Vials","offer_id":50240948175091,"sku":"pp-tsa-20-3v","price":229.5,"currency_code":"USD","in_stock":false},{"title":"20mg \/ 5 Vials","offer_id":50240948207859,"sku":"pp-tsa-20-5v","price":337.5,"currency_code":"USD","in_stock":false},{"title":"20mg \/ 10 Vials","offer_id":50279142064371,"sku":null,"price":585.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0839\/9857\/2787\/files\/tesamorelin-approved-wider-panel_c36af3ab-ffc4-42c8-b979-ba3c087146cb.png?v=1788221485","url":"https:\/\/prestigepeptides.us\/products\/pp-11","provider":"Prestige Peptides","version":"1.0","type":"link"}