{"product_id":"pp-06","title":"GHK-Cu","description":"\u003cp\u003eGHK-Cu (copper tripeptide-1) is a naturally occurring copper-binding peptide studied in laboratory research for its interaction with cellular repair and gene-expression pathways. Research models have examined its role in collagen-synthesis signaling, antioxidant-pathway activity, and tissue-remodeling processes. Supplied as lyophilized material for qualified in-vitro research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCompound specifications:\u003c\/strong\u003e Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.\u003c\/p\u003e\u003cdiv class=\"pp-product-notes\"\u003e\n\u003cdiv class=\"pp-product-notes__item\"\u003e\n\u003cp class=\"pp-product-notes__label\"\u003eHandling and storage\u003c\/p\u003e\n\u003cp\u003eSupplied as lyophilized (freeze-dried) material. Store under the conditions printed on the product label and use laboratory handling procedures appropriate to your work. Every vial is labeled with lot information for batch traceability.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pp-product-notes__item\"\u003e\n\u003cp class=\"pp-product-notes__label\"\u003eResearch use notice\u003c\/p\u003e\n\u003cp\u003eReserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\n\u003ch2\u003eWhat is GHK-Cu?\u003c\/h2\u003e\n\u003cp\u003eGHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine (GHK), a tripeptide first identified in human plasma in the 1970s. GHK's high affinity for copper ions and its decline with age in circulation — documented in the literature — made the complex a long-running subject of skin, remodeling, and gene-expression research.\u003c\/p\u003e\n\u003cp\u003ePublished studies examine GHK-Cu across cell-culture, tissue, and animal models, including work on extracellular-matrix organization and broad gene-expression modulation. It is supplied here as high-purity lyophilized material strictly for qualified research use.\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action — Research Overview\u003c\/h2\u003e\n\u003cp\u003eIn research models, GHK acts as a copper-delivery and -modulation peptide: it binds Cu(II) with high affinity and is studied for how that complex influences copper-dependent enzymes, antioxidant-pathway markers, and matrix-metalloproteinase\/TIMP balance in tissue models.\u003c\/p\u003e\n\u003cp\u003eGene-expression studies (notably the Broad Institute connectivity-map analyses discussed in the literature) report GHK-associated modulation of a wide panel of genes involved in tissue organization and stress response — a systems-level profile rather than single-target activity.\u003c\/p\u003e\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCopper-transport and metallopeptide chemistry research\u003c\/li\u003e\n\u003cli\u003eExtracellular-matrix and remodeling-pathway studies\u003c\/li\u003e\n\u003cli\u003eSkin and fibroblast research models\u003c\/li\u003e\n\u003cli\u003eGene-expression modulation studies\u003c\/li\u003e\n\u003cli\u003eAntioxidant-pathway and stress-response research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eGHK-Cu Specifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilized powder in sealed 3 mL glass vial (50mg \/ 100mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e49557-75-7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChemical Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC14H23CuN6O4 (complex)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 402.9 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e71587328\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCopper tripeptide-1, Glycyl-L-histidyl-L-lysine copper(II) complex\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStore lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eLaboratory Handling \u0026amp; Storage\u003c\/h2\u003e\n\u003cp\u003eStandard handling for lyophilized metallopeptides: sterile technique, PPE, protection from light and moisture, documented lot tracking.\u003c\/p\u003e\n\u003ch2\u003eCertificate of Analysis \u0026amp; Quality Assurance\u003c\/h2\u003e\n\u003cp\u003eEvery batch of GHK-Cu is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: \u003ca href=\"https:\/\/verify.janoshik.com\/tests\/169279-GHKCU_50mg_CU50_APD9PDN5F98T\" target=\"_blank\" rel=\"noopener\"\u003eview batch COA\u003c\/a\u003e. Documentation of lot number, test date, and method accompanies each batch.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eThe potential of GHK as an anti-aging peptide. \u003cem\u003eAging Pathobiol Ther\u003c\/em\u003e. 2020. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35083444\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 35083444\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eGHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. \u003cem\u003eBiomed Res Int\u003c\/em\u003e. 2015. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26236730\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 26236730\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eNote: GHK-Cu is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eShipping, Handling \u0026amp; Guarantee\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast U.S. shipping:\u003c\/strong\u003e Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLab safety profile:\u003c\/strong\u003e Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder guarantee:\u003c\/strong\u003e If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our \u003ca href=\"\/policies\/refund-policy\"\u003eReturn \u0026amp; Refund Policy\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Prestige Peptides","offers":[{"title":"50mg \/ 1 Vial","offer_id":50520205885683,"sku":"pp-k6-50-1v","price":29.0,"currency_code":"USD","in_stock":true},{"title":"50mg \/ 3 Vials","offer_id":50226741706995,"sku":"pp-k6-50-3v","price":73.95,"currency_code":"USD","in_stock":true},{"title":"50mg \/ 5 Vials","offer_id":50226741739763,"sku":"pp-k6-50-5v","price":108.75,"currency_code":"USD","in_stock":true},{"title":"50mg \/ 10 Vials","offer_id":50279141572851,"sku":null,"price":188.5,"currency_code":"USD","in_stock":true},{"title":"100mg \/ 1 Vial","offer_id":50520205918451,"sku":"pp-k6-100-1v","price":50.0,"currency_code":"USD","in_stock":true},{"title":"100mg \/ 3 Vials","offer_id":50226741805299,"sku":"pp-k6-100-3v","price":127.5,"currency_code":"USD","in_stock":true},{"title":"100mg \/ 5 Vials","offer_id":50226741838067,"sku":"pp-k6-100-5v","price":187.5,"currency_code":"USD","in_stock":true},{"title":"100mg \/ 10 Vials","offer_id":50279141605619,"sku":null,"price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0839\/9857\/2787\/files\/ghk-cu-approved-wider-panel_8603bf2a-7134-47e0-b3d3-3718b3618b37.png?v=1788221447","url":"https:\/\/prestigepeptides.us\/products\/pp-06","provider":"Prestige Peptides","version":"1.0","type":"link"}