{"product_id":"pp-05","title":"KPV","description":"\u003cp\u003eKPV (Lys-Pro-Val) is a tripeptide corresponding to the C-terminal sequence of alpha-MSH. Laboratory research has explored its role in inflammatory-pathway models, including NF-kB signaling and cytokine-activity studies in vitro. Supplied as lyophilized material for qualified research applications.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCompound specifications:\u003c\/strong\u003e Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.\u003c\/p\u003e\u003cdiv class=\"pp-product-notes\"\u003e\n\u003cdiv class=\"pp-product-notes__item\"\u003e\n\u003cp class=\"pp-product-notes__label\"\u003eResearch use notice\u003c\/p\u003e\n\u003cp\u003eReserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\n\u003ch2\u003eWhat is KPV?\u003c\/h2\u003e\n\u003cp\u003eKPV (Lys-Pro-Val) is the C-terminal tripeptide of α-melanocyte-stimulating hormone (α-MSH 11-13). It retains a portion of the parent hormone's studied biological activity in research models while lacking the melanocortin-receptor-driven pigmentary effects associated with the full-length peptide — a separation that has made it a distinct research subject.\u003c\/p\u003e\n\u003cp\u003eThe KPV literature concentrates on inflammatory-signaling research, including intestinal and epithelial models. It is supplied here as high-purity lyophilized material strictly for qualified research use.\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action — Research Overview\u003c\/h2\u003e\n\u003cp\u003eResearch models examine KPV's influence on inflammatory-pathway markers — including NF-κB and cytokine signaling — through mechanisms studied as largely independent of classical melanocortin-receptor activation. Cellular uptake via the PepT1 transporter is a recurring theme in the intestinal-epithelium literature.\u003c\/p\u003e\n\u003cp\u003eStudies describe pathway-modulation effects on immune-signaling cascades in cell and animal models, positioning KPV as a small, transporter-accessible probe for inflammatory-pathway research.\u003c\/p\u003e\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eInflammatory-signaling and NF-κB pathway research\u003c\/li\u003e\n\u003cli\u003eIntestinal-epithelium and PepT1-transport studies\u003c\/li\u003e\n\u003cli\u003eCytokine-signaling models\u003c\/li\u003e\n\u003cli\u003eα-MSH fragment comparative research\u003c\/li\u003e\n\u003cli\u003eEpithelial-barrier research models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eKPV Specifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilized powder in sealed 3 mL glass vial (10mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e67727-97-3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChemical Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC16H30N4O4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≈ 342.4 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e125672\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eα-MSH(11-13), Lys-Pro-Val, KPV tripeptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStore lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eLaboratory Handling \u0026amp; Storage\u003c\/h2\u003e\n\u003cp\u003eStandard small-peptide handling: sterile technique, PPE, moisture and light protection, and lot documentation.\u003c\/p\u003e\n\u003ch2\u003eCertificate of Analysis \u0026amp; Quality Assurance\u003c\/h2\u003e\n\u003cp\u003eEvery batch of KPV is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: \u003ca href=\"https:\/\/verify.janoshik.com\/tests\/169746-KPV_1omgKP10_XQ734JDRM7YM\" target=\"_blank\" rel=\"noopener\"\u003eview batch COA\u003c\/a\u003e. Documentation of lot number, test date, and method accompanies each batch.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003ealpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells. \u003cem\u003eJ Invest Dermatol\u003c\/em\u003e. 2004. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15102092\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 15102092\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eEffects of the COOH-terminal tripeptide alpha-MSH(11-13) on corneal epithelial wound healing: role of nitric oxide. \u003cem\u003eExp Eye Res\u003c\/em\u003e. 2006. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16965771\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 16965771\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eNote: KPV is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eShipping, Handling \u0026amp; Guarantee\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast U.S. shipping:\u003c\/strong\u003e Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLab safety profile:\u003c\/strong\u003e Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder guarantee:\u003c\/strong\u003e If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our \u003ca href=\"\/policies\/refund-policy\"\u003eReturn \u0026amp; Refund Policy\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Prestige Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50520206278899,"sku":"pp-kp3-10-1v","price":40.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50226741215475,"sku":"pp-kp3-10-3v","price":102.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 5 Vials","offer_id":50226741248243,"sku":"pp-kp3-10-5v","price":150.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50279141540083,"sku":null,"price":260.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0839\/9857\/2787\/files\/kpv-approved-wider-panel_1cc6fdc7-eec3-4fde-9025-b2c3f4a1a2a0.png?v=1788221454","url":"https:\/\/prestigepeptides.us\/products\/pp-05","provider":"Prestige Peptides","version":"1.0","type":"link"}