{"product_id":"pp-02","title":"TB-500","description":"\u003cp\u003eTB-500 is a synthetic peptide fragment based on the active region of thymosin beta-4. Research literature has examined its role in actin-binding activity, cell-migration models, and tissue-repair signaling pathways. Supplied as lyophilized material for qualified in-vitro research.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCompound specifications:\u003c\/strong\u003e Lyophilized powder in sealed vials. Purity verified at ≥99% by independent third-party HPLC analysis. Store in a cool, dry environment; refrigerate after reconstitution per standard laboratory protocol.\u003c\/p\u003e\u003cdiv class=\"pp-product-notes\"\u003e\n\u003cdiv class=\"pp-product-notes__item\"\u003e\n\u003cp class=\"pp-product-notes__label\"\u003eResearch use notice\u003c\/p\u003e\n\u003cp\u003eReserved for qualified in-vitro laboratory research only. Not for human consumption, veterinary use, clinical, diagnostic, or therapeutic use. Purchasers must be 21 years of age or older and accept the Research Use Only Agreement before ordering.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\n\u003ch2\u003eWhat is TB-500?\u003c\/h2\u003e\n\u003cp\u003eTB-500 is a synthetic peptide based on the active region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid actin-binding protein found in virtually all mammalian cell types studied. The TB-500 designation in research supply refers to the synthetic fragment built around Tβ4's characterized actin-binding motif.\u003c\/p\u003e\n\u003cp\u003eThymosin Beta-4 has a broad published literature in cell-migration, angiogenesis, and tissue-organization research models, and TB-500 is studied as its practical research proxy. It is supplied here as high-purity lyophilized material strictly for qualified research use.\u003c\/p\u003e\n\u003ch2\u003eMechanism of Action — Research Overview\u003c\/h2\u003e\n\u003cp\u003eThe parent protein's best-characterized research role is regulation of actin dynamics: Tβ4 binds monomeric G-actin and influences the balance between actin polymerization and sequestration, a core determinant of cell shape, motility, and migration in experimental systems.\u003c\/p\u003e\n\u003cp\u003eResearch models additionally examine Tβ4-region peptides in relation to angiogenic signaling, extracellular-matrix organization, and inflammatory-response modulation — typically framed as multi-pathway effects rather than single-receptor pharmacology.\u003c\/p\u003e\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eActin-dynamics and cytoskeletal-organization research\u003c\/li\u003e\n\u003cli\u003eCell-migration and motility studies\u003c\/li\u003e\n\u003cli\u003eAngiogenic-signaling research models\u003c\/li\u003e\n\u003cli\u003eSoft-tissue and extracellular-matrix research\u003c\/li\u003e\n\u003cli\u003eComparative studies with BPC-157 and blended-peptide models\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTB-500 Specifications\u003c\/h2\u003e\n\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormat\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilized powder in sealed 3 mL glass vial (10mg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParent Compound\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eThymosin Beta-4 — CAS 77591-33-4; formula C212H350N56O78S; ≈ 4963.4 g\/mol; PubChem CID 45382195\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eThymosin Beta-4 fragment, Tβ4 peptide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eStore lyophilized at −20°C, sealed, protected from light and moisture. Refrigerate after reconstitution per standard laboratory protocol.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\n\u003ch2\u003eLaboratory Handling \u0026amp; Storage\u003c\/h2\u003e\n\u003cp\u003eStandard lyophilized-peptide handling: sterile technique, PPE, moisture protection, and lot documentation.\u003c\/p\u003e\n\u003ch2\u003eCertificate of Analysis \u0026amp; Quality Assurance\u003c\/h2\u003e\n\u003cp\u003eEvery batch of TB-500 is verified by independent third-party HPLC analysis (identity and purity) before it ships. The certificate of analysis for the current batch is linked on this page and can be reviewed here: \u003ca href=\"https:\/\/verify.janoshik.com\/tests\/169295-TB500_10mg_NA17Q3RL9LPV\" target=\"_blank\" rel=\"noopener\"\u003eview batch COA\u003c\/a\u003e. Documentation of lot number, test date, and method accompanies each batch.\u003c\/p\u003e\n\u003ch2\u003eReferences\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eThymosin β(4) and β(10) Expression in Human Organs during Development: A Review. \u003cem\u003eCells\u003c\/em\u003e. 2024. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38994967\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 38994967\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eThymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. \u003cem\u003eInt Immunopharmacol\u003c\/em\u003e. 2023. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36709593\/\" target=\"_blank\" rel=\"noopener\"\u003ePMID: 36709593\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cem\u003eNote: TB-500 is supplied strictly for laboratory research use only. It is not approved for human or veterinary use, and nothing on this page is medical advice or a health claim. All described findings reflect preclinical or published research contexts.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eShipping, Handling \u0026amp; Guarantee\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast U.S. shipping:\u003c\/strong\u003e Orders placed before 2:00 PM CT ship the same business day from Minneapolis, MN. Free shipping on orders over $100.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLab safety profile:\u003c\/strong\u003e Supplied for laboratory research use only. Handle using appropriate personal protective equipment in a suitable laboratory setting. Not for human or veterinary use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrder guarantee:\u003c\/strong\u003e If your order arrives damaged, incorrect, or incomplete, contact us within 48 hours of delivery with photos and we will make it right. See our \u003ca href=\"\/policies\/refund-policy\"\u003eReturn \u0026amp; Refund Policy\u003c\/a\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Prestige Peptides","offers":[{"title":"10mg \/ 1 Vial","offer_id":50520206311667,"sku":"pp-tb5-10-1v","price":40.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 3 Vials","offer_id":50226739380467,"sku":"pp-tb5-10-3v","price":102.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 5 Vials","offer_id":50226739413235,"sku":"pp-tb5-10-5v","price":150.0,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 10 Vials","offer_id":50279141245171,"sku":null,"price":260.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0839\/9857\/2787\/files\/tb-500-approved-wider-panel_40a7e0be-5985-4869-8651-eef4a51c3362.png?v=1788221479","url":"https:\/\/prestigepeptides.us\/products\/pp-02","provider":"Prestige Peptides","version":"1.0","type":"link"}